Biotech Investment Surges in 2020

Roshan Chikarmane. Ph.D. Student JHU On March 5, six days before the WHO officially recognized COVID-19 as a global pandemic1, the United States recorded 174 total confirmed cases within its borders2. On that same day, the investment team at Sequoia Capital – a lauded venture capital firm with approximately $1.4 trillion in assets under management […]

Performance and early clinical results of Arvinas’ ARV-110

Authors: Muzzammil Ahmadzada1, Waqas Haque2, and Muhammad A Saeed3 Affiliations: 1Johns Hopkins University; 2University of Texas Southwestern Medical School; 3 Zanvyl Krieger School of Arts and Sciences, Johns Hopkins University  Disclosures: The authors have no financial conflicts of interest. The first section of this article briefly explains prostate cancer and the technology that the ARV-110 […]

An overview of Ganaxolone for treatment of rare seizure disorders

Authors: Muzzammil Ahmadzada1 and Waqas Haque2, MPH, MPHil Affiliations: 1Johns Hopkins University; 2University of Texas Southwestern Medical School   Disclosures: The authors have no financial conflicts of interest. Ganaxolone is an experimental drug under development from Marinus Pharmaceuticals, a clinical stage pharmaceutical company founded in 2003 that focuses on treating drug-resistant seizures and neuropsychiatric disorders.1 […]

COVID-19 Surveillance & Consumer-Driven Healthcare

by Tawny Hammett, M.S. JHU Alumna The COVID-19 pandemic has transcended a mere influenza-like disease, showcasing a range of severity from mild cold symptoms to multi-organ failure and death1. Given the spectrum of COVID-19’s virulence, testing is a crucial epidemic surveillance strategy to detect, contain, and mitigate viral spread throughout the population. In April 2020, […]

New Molecular Tool for Mitochondrial Genome Editing

by Yazmin I. Rovira Gonzalez, Ph.D., JHU Alumna CRISPR-Cas9 technology is a powerful tool for editing genomes, as it allows researchers to alter DNA sequences and modify gene function. It can potentially correct genetic defects, treat, and prevent the spread of diseases. CRISPR works alongside different types of “Cas” proteins found in bacteria, where they […]